Essed by continuous glucose monitoring, biomarker of TLR4 medchemexpress beta-cell function and biochemical
Essed by continuous glucose monitoring, biomarker of beta-cell function and biochemical parameter Metformin (n = 36) Parameter of glucose control FPG baseline (mmol/l) FPG week 36 (mmol/l) FPG SMYD3 custom synthesis adjust (mmol/l) PPG 1200 baseline (mmol/l) PPG 1200 week 36 (mmol/l) PPG 1200 change (mmol/l) HbA1c baseline ( ) HbA1c week 36 ( ) HbA1c adjust ( ) Interstitial glucose measurements AUC baseline (mmol l-1 min) AUC week 36 (mmol l-1 min) AUC adjust (mmol l-1 min) incAUC baseline (mmol l-Insulin glargine (n = 39)p8.7 1.6 7.2 1 -1.four 1.5 10.3 two.8 8.4 2.1 -1.six two.five six.9 0.four six.31 0.four -0.6 0.41 2387.0 500.three 1971.8 337.8 -416.1 537.6 55.four 30.2 49.six 25.0 -5.eight 31.eight eight.three 1.7 6.9 1.2 -1.4 1.eight three.3 0.9 2.9 1.1 -0.4 1.7 1.six 0.eight 1.three 0.five -0.2 0.7 8.6 six.two five.eight four.6 -3 4.1 26.8 16.0 20.four 19.9 -6.6 14.3 1.0 0.5 0.9 0.four -0.1 0.three 2.7 1.1 two.6 1.3 0 0.7 90.six 51.two 71.6 43.0 -19.two 26.0 445.two 303 364.6 285 -79.9 216.9 22.two 29.1 24.7 27.1 three.0 eight.9.two 2.1 6.1 1.1 -3.1 two.5 11.1 4.five 8.three 2.5 -2.eight three.two 7.2 0.7 six.36 0.four -0.8 0.69 2671.five 598.5 2000.3 313.1 -671.2 507.9 73.9 39.9 68.3 24.6 -5.7 40.four 9.4 2.1 7.0 1.0 -2.4 1.7 four.0 1.1 3.7 1.0 -0.three 1.3 1.eight 0.6 1.7 0.5 -0.07 0.7 13.0 13.5 5.four five.0 -7.six ten.eight 37.eight 32.two 26.eight 29 -11.1 26.8 0.9 0.4 0.5 0.three -0.four 0.four two.4 1.0 two.2 1.0 -0.2 0.eight 85.1 48.six 104.4 62.9 19.two 47.9 401.eight 296.2 448.8 371.9 46.six 275.six 12.five 7.5 20.7 11.eight 8.2 9.0.297 0.001 0.001 0.415 0.832 0.106 0.045 0.478 0.087 0.029 0.774 0.039 0.027 0.002 0.989 0.015 0.573 0.022 0.001 0.001 0.676 0.121 0.001 0.45 0.023 0.35 0.001 0.069 0.259 0.019 0.453 0.001 0.001 0.274 0.274 0.348 0.733 0.01 0.001 0.487 0.416 0.06 0.063 0.410 0.min)incAUC week 36 (mmol l-1 min) incAUC transform (mmol l-1 min) Imply IG baseline (mmol/l) Imply IG week 36 (mmol/l) Imply IG adjust (mmol/l) MAGE baseline MAGE week 36 MAGE change SD baseline SD week 36 SD adjust Parameter of beta-cell function Proinsulin 00 baseline (pmol/l) Proinsulin 00 wk 36 (pmol/l) Proinsulin 00 transform (pmol/l) Proinsulin 120 baseline (pmol/l) Proinsulin 1200 week 36 (pmol/l) Proinsulin 1200 adjust (pmol/l) C-peptide 00 baseline (nmol/l) C-peptide 00 week 36 (nmol/l) C-peptide 0 change (nmol/l) C-peptide 1200 baseline (nmol/l) C-peptide 1200 week 36 (nmol/l) C-peptide 1200 change (nmol/l) Insulin 00 baseline (pmol/l) Insulin 00 week 36 (pmol/l) Insulin 0 modify (pmol/l) Insulin 1200 baseline (pmol/l) Insulin 1200 week 36 (pmol/l) Insulin 1200 transform (pmol/l) Insulin/proinsulin 1200 baseline Insulin/proinsulin 120 week 36 Insulin/proinsulin 1200 change0 0 0Acta Diabetol (2013) 50:58795 Table 2 continued Metformin (n = 36) HOMA B baseline HOMA B week 36 HOMA B alter HOMA IR baseline HOMA IR week 36 HOMA IR change Blood flow measurements Pre-ischemic BF baseline (U) Pre-ischemic BF week 36 (U) MaxBF baseline (U) MaxBF week 36 (U) MaxBF modify (U) Security parameter Duration glucose \3.9 baseline (min) Duration glucose \3.9 week 36 (min) Self assessed BG \3.1 mmol/l (n) Gastrointestinal complaints (n) 23.3 13.4 25.2 13.4 81.9 48 90.7 43 eight.eight 31.5 1.5 9.two 11.2 41.4 four 10 25.8 14.7 26.6 14.7 99.0 29.1 89.1 32.4 -9.9 39.6 3.0 13.1 13.six 46.five 14 0 49.four 34.five 56.three 34.five 4.4 19.5 5.0 three.7 three.two 2.0 -1.8 1.8 Insulin glargine (n = 39) 48.2 36.7 128 99 77.2 97.8 4.9 3.eight 4.0 two.four -1.1 3.0 p0.893 0.001 0.001 0.893 0.116 0.239 0.350 0.766 0.091 0.697 0.042 0.592 0.468 0.045 0.AUC region beneath the interstitial glucose curve, incAUC incremental area below the interstitial glucose curve from the test meal, Imply IG mean interstitial glucose values, SD normal deviation of interstiti.
