Product Name: EPZ-6438
Product Description: EPZ-6438 is a potent, selective and orally bioavailable inhibitor of methyltransferase EZH2 with a Ki value of 2.5 nM. EPZ-6438 also shows a 35-fold selectivity versus EZH1 (IC50 392 nM) and >4,500-fold selectivity relative to 14 other histone methyltrMedchemexpress.com
Chemical Formula:
Molecular Weight: 572.74
‘&“CAS NO: 1434048-34-6 GDC-0853
Purity: 98%
Appearance:
Chemical Name: N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-4-methyl-4-(4-morpholinylmethyl)-[1,1-biphenyl]-3-carboxamideWnt/Hedgehog/Notch_Compound_Library inhibitors
Solubility: Up to 10 nM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: PubMed ID:http://meeting.ascopubs.org/cgi/content/abstract/27/15S/3510
