Product Name: CX-5461 | RNA Pol I inhibitor
Product Description: CX-5461 is a potent, orally bioavailable small molecule inhibitor of rRNA synthesis in cancer cells. It selectively inhibits rRNA synthesis by polymerase I (Pol I) in the nucleolus, but does not inhibit mRNA synthesis by RNA Polymerase II (Pol II), DNA reWeb Site click
Chemical Formula:
Molecular Weight: 513.61
‘&“CAS NO: 1218942-37-0 GKT137831
Purity: 98%
Appearance:
Chemical Name: 5H-Benzothiazolo[3,2-a][1,8]naphthyridine-6-carboxamide, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-N-[(5-methyl-2-pyrazinyl)methyl]-5-oxo-NF-κB_Signaling_Compound_Library inhibitors
Solubility: Up to 1 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22989411
