Product Name: Spautin-1 | Autophagy inhibitor
Product Description: Spautin-1 is a specific and potent autophagy inhibitor (IC50=0.74µM). It promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin specific peptidases, USP10 and USP13, that target the Beclin1 subunit of Vps34 complexes. SinMedchemexpress
Chemical Formula: C15H11F2N3
Molecular Weight: 271.26
‘&“CAS NO: 1078166-57-0 PF-04418948
Purity: 98%
Appearance: White solid
Chemical Name: 6-fluoro-N-(4-fluorobenzyl)quinazolin-4-amineMembrane_Transporter/Ion_Channel_Compound_Library inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17092993