Product Name: AGI-5198 (IDH-C35) | IDH1 inhibitor
Product Description: AGI-5198 (IDH-C35) is a potent and selective isocitrate dehydrogenase 1 (IDH1) inhibitor specifically against R132H/C mutants (mIDH1) with IC50 at 100 nM range. AGI-5198 does not inhibit wild-type IDH1 or any of the examined IDH2 isoforms (IC50 > 100 &Web Site click
Chemical Formula: C27H31FN4O2
Molecular Weight: 462.56
‘&“CAS NO: 1474110-21-8 ROR gama modulator 1
Purity: 98%
Appearance: White
Chemical Name: N-cyclohexyl-2-(N-(3-fluorophenyl)-2-(2-methyl-1H-imidazol-1-yl)acetamido)-2-(o-tolyl)acetamideNeurological Disease inhibitors
Solubility: Up to 25 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder or DMSO solution at -20oC desiccated.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16570908
