Product Name: ABT-263 (Navitoclax) | Bcl-2 family inhibitor
Product Description: ABT-263 is an orally-available Bcl-2 family inhibitor with Ki values of < 1 nM for Bcl-2, Bcl-xL, and Bcl-w. ABT-263 disrupts key Bcl interactions with proteins such as Bim, inducing apoptosis. Despite being a Bad-like Bh3 mimetic, ABT-263 has been shoWeb Site:Medchemexpress
Chemical Formula: C47H55ClF3N5O6S3
Molecular Weight: 974.61
‘&“CAS NO: 918504-65-1 Vemurafenib
Purity: 98%
Appearance: white
Chemical Name: (R)-4-(4-((4-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamideVD_VDR inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.nature.com/nature/journal/v447/n7146/abs/nature05859.html