Product Name: LY2157299 | TGF-β receptor (TβR) inhibitor
Product Description: LY2157299, a specific and potent TGF-β receptor (TβR) inhibitor that competitively binds to the active site of its kinase domain1, inhibiting TGF-β-mediated SMAD2 phosphorylation/activation and down streaming signaling. LY2157299 inhibitedMedchemexpress.com
Chemical Formula: C22H19N5O
Molecular Weight: 369.42
‘&“CAS NO: 1195765-45-7 Dabrafenib
Purity: 98%
Appearance: Off white solid
Chemical Name: 4-[2-(6-Methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-quinoline-6-carboxylic acid amide(beta)-catenin inhibitors
Solubility: Up to 50 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: PubMed ID:http://jpet.aspetjournals.org/content/292/1/288.short
