Product Name: GSK2126458 | PI3K/mTOR inhibitor
Product Description: GSK2126458 is an orally available, pyridazine-quinoline-based inhibitor of of p110?, p110?, p110?, p110?, mTORC1, and mTORC2 with Ki of 0.019 nM, 0.13 nM, 0.024 nM, 0.06 nM, 0.18 nM and 0.3 nM, respectively. [1] In mechanistic assays, GSK2126458 induced sWeb Site click
Chemical Formula: C25H17F2N5O3S
Molecular Weight: 505.5
‘&“CAS NO: 154229-18-2 Abiraterone (acetate)
Purity: 98%
Appearance: White
Chemical Name: 2,4-difluoro-N-(2-methoxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamideItk inhibitors
Solubility: Up to 100mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21456623
