Product Name: LDN-193189 | BMP type I receptors ALK2/3 inhibitor
Product Description: LDN193189 is a highly potent BMP inhibitor, prevents Smad1, Smad5, and Smad8 phosphorylation through inhibition of BMP type I receptors ALK2 (IC50=5nM) and ALK3 (IC50=30 nM). Its inhibitions against ALK4, ALK5, and ALK7 are weak (IC50 >500 nM). As BMP Medchemexpress.com
Chemical Formula: C25H22N6 C25H22N6
Molecular Weight: 406.48
‘&“CAS NO: 1197953-54-0 Brigatinib
Purity: 98%
Appearance: Yellow solid
Chemical Name: 4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinolinePTEN inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22323721
