Product Name: GDC-0349 | mTOR inhibitor
Product Description: GDC-0349 is an ATP-competitive, potent and selective inhibitor of mTOR with an Ki value of 3.8 nM. It has ~800-fold selectivity over PI3Ka and in PC3 cells exhibits an EC50 of 270 nM. Additionally GDC-0349 showed less than25% inhibition in a panel of 266 Web Site：Medchemexpress
Chemical Formula: C24H32N6O3
Molecular Weight: 452.55
‘&“CAS NO: 1629249-40-6 Integrin Antagonist 1 (hydrochloride)
Purity: 98%
Appearance: light yellow
Chemical Name: (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)ureaMALT1 inhibitors
Solubility: Up to 50 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.nature.com/npp/journal/v37/n2/abs/npp2011191a.html
