Product Name: RO4929097 | γ-secretase inhibitor
Product Description: RO4929097 is a potent and selective small molecule inhibitor of γ-secretase (IC50=4nM), producing inhibitory activity of Notch signaling in tumor cells. It inhibits Notch processing in tumor cells as measured by the reduction of intracellular Notch Medchemexpress.com
Chemical Formula: C22H20F5N3O3
Molecular Weight: 469.40
‘&“CAS NO: 1453848-26-4 GDC-0994
Purity: 98%
Appearance: White solid
Chemical Name: 2,2-dimethyl-N-((S)-6-oxo-6,7-dihydro-5H-dibenzo[b, d]azepin-7-yl)-N′-(2,2,3,3,3-pentafluoro-propyl)-malonamideCOMT inhibitors
Solubility: Up to 50 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/8457165