Product Name: PCI-32765 (Ibrutinib) | BTK inhibitor
Product Description: PCI-32765 (Ibrutinib) is a selective and irreversible pyrrolopyrimidine-based inhibitor of BTK with IC50 of 0.5 nM. [1] PCI-32765 binds irreversibly to Cys-481 in BTK and thus is only active with other kinases with such a modifiable cysteine residue. In DWeb Site click
Chemical Formula: C25H24N6O2
Molecular Weight: 440.5
‘&“CAS NO: 410528-02-8 Palovarotene
Purity: 99%
Appearance: White
Chemical Name: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-oneMembrane Transporter_Ion Channel inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/24712661
