Product Name: SGX523 | cMET inhibitor
Product Description: SGX523 is an ATP-competitive, triazolopyridazine-based inhibitor of MET at an IC50 of 4 nM. SGX523 has higher affinity for the unphosphorylated form of MET (Ki = 2.7 nM) than the more active phospho-enzyme (Ki = 23 nM). In a broad panel of 213 kinases, SGMedchemexpress
Chemical Formula: C18H13N7S
Molecular Weight: 359.41
‘&“CAS NO: 1353625-73-6 Presatovir
Purity: 98%
Appearance: Pale Pink
Chemical Name: 6-(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylthio)quinolineMNK inhibitors
Solubility: Up to 5 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15520202
