Product Name: LY2784544 | JAK2 inhibitor
Product Description: LY-2784544 is an orally-available, imidazolopyridazine-based inhibitor of the JAK2-V617F mutation, the most common abnormality in Bcr-Abl-negative myeloid proliferative neoplasms. [1] Inhibition in Ba/F3 cells was found to be 55 nM. [2] Inhibition of wildMedchemexpress.com
Chemical Formula: C23H25ClFN7O
Molecular Weight: 469.94
‘&“CAS NO: 1456858-58-4 HG-9-91-01
Purity: 98%
Appearance: White
Chemical Name: 3-(4-chloro-2-fluorobenzyl)-2-methyl-N-(3-methyl-1H-pyrazol-5-yl)-8-(morpholinomethyl)imidazo[1,2-b]pyridazin-6-amineMAPK_ERK Pathway inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://eurekaselect.com/87309/article/inhibition-tgf-signaling-treatment-tumor-metastasis-and-fibrotic-diseases
