Product Name: NVP-TAE684 | ALK inhibitor
Product Description: NVP-TAE684 is an aminopyrimidine-based, ATP-competitive inhibitor of ALK (IC50, 3 nM) with additional activity vs Flt3 and Tie2 at values of 3 nM, and 12 nM, respectively. Despite ALKs high sequence homology with insulin receptor kinase (InsR), cellular Medchemexpress
Chemical Formula: C30H40ClN7O3S
Molecular Weight: 614.2
‘&“CAS NO: 451493-31-5 AV-412
Purity: 98%
Appearance: Pale Yellow
Chemical Name: 5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamineNeurokinin Receptor inhibitors
Solubility: Up to 15 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.sciencedirect.com/science/article/pii/S0960894X01805412
