Product Name: HTH-01-015
Chemical Name: 4,5,13-trimethyl-2-((1-(piperidin-4-yl)-1H-pyrazol-4-yl)amino)-5H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6(13H)-one
SMILES Code: CC1=C2C(=NC(=N1)NC3=CN(N=C3)C4CCNCC4)N(C5=CC6=CC=CC=C6C=C5C(=O)N2C)C
CAS NO: 123171-59-5 Product: Trandolapril
Synonym: HTH 01 015
Chemical Formula: C26H28N8O
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).CFTR inhibitors
Solubility: Soluble in DMSO
Background Description: HTH-01-015 is a potent and selective inhibitor of NUAK1 kinase (IC₅₀ =100 nM); only weakly inhibits NUAK2 (IC₅₀ of >10 μM) and does not significantly inhibit the activity of 139 other kinases that were tested including ten AMPK family members.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/8729205
