Product Name: PND-1186
Chemical Name: 2-((2-((2-methoxy-4-morpholinophenyl)amino)-5-(trifluoromethyl)pyridin-4-yl)amino)-N-methylbenzamide
SMILES Code: O=C(NC)C1=CC=CC=C1NC2=CC(NC3=C(OC)C=C(N4CCOCC4)C=C3)=NC=C2C(F)(F)F
CAS NO: 100427-26-7 Product: Homoharringtonine
Synonym: SR-2516; PND 1186; PND1186; SR 2516; SR2516; VS-4718; VS 4718; VS4718
Chemical Formula: C25H26F3N5O3
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Orexin Receptor OX Receptor) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: PND-1186 (SR-2156 and VS-4718) is a potent FAK inhibitor with a 50% inhibitory concentration (IC50) of 1.5 nM in vitro. PND-1186 has an IC50 of ~100 nM in breast carcinoma cells.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/10870095
