Product Name: AZD3839
Chemical Name: (3S)-3-(2-(difluoromethyl)pyridin-4-yl)-7-fluoro-3-(3-(pyrimidin-5-yl)phenyl)isoindolin-1-amine
SMILES Code: NC1N[C@@](C2=CC=CC(C3=CN=CN=C3)=C2)(C4=CC(C(F)F)=NC=C4)C5=C1C(F)=CC=C5
CAS NO: 157810-81-6 Product: Zofenopril (calcium)
Synonym: AZD-3839; AZD 3839
Chemical Formula: C24H18F3N5
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Histone Demethylase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: AZD3839 is a potent and selective BACE1 inhibitor, which is clinical candidate for the treatment of Alzheimer disease. AZD 3839 inhibits BACE1 activity, Aβ and sAPPβ release from modified and wild-type human SH-SY5Y cells and mouse N2A cells as well as frPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18771728
