Product Name: Vemurafenib
Chemical Name: N-(3-(5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
SMILES Code: CCCS(=O)(NC1=CC=C(F)C(C(C2=CNC3=NC=C(C4=CC=C(Cl)C=C4)C=C32)=O)=C1F)=O
CAS NO: 566-48-3 Product: UK 14,304
Synonym: PLX4032; PLX 4032; PLX-4032; RG7204 ; RG7204 ; RG 7204 ; RO5185426; RO 5185426; RO5185426
Chemical Formula: C23H18ClF2N3O3S
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).AMPK inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Vemurafenib (PLX4032, RG7204, RO5185426) is an orally bioavailable, ATP-competitive, small-molecule inhibitor of BRAF (V600E) kinase with potential antineoplastic activity. It selectively binds to the ATP-binding site of BRAF (V600E) kinase and inhibits iPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18656896
