Product Name: SU-5614
Chemical Name: (3Z)-5-Chloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
SMILES Code: O=C1NC2=C(C=C(Cl)C=C2)/C1=C/C3=C(C)C=C(C)N3
CAS NO: 591778-68-6 Product: Cysteine Protease inhibitor (hydrochloride)
Synonym: SU5614; SU 5614
Chemical Formula: C15H13ClN2O
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Cell_Counting_Kit-8 inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: SU5-614 is a potent and selective FLT3 inhibitor. SU5614 has inhibitory activity for FLT3 and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3. SU5614 reverts the anPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18656556