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Product Name: Acalabrutinib
Chemical Name: (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide
SMILES Code: O=C(NC1=NC=CC=C1)C2=CC=C(C3=C4C(N)=NC=CN4C([C@H]5N(C(C#CC)=O)CCC5)=N3)C=C2
CAS NO: 146-68-9 Product: ABTS (diammonium salt)
Synonym: ACP-196; ACP196; ACP 196
Chemical Formula: C26H23N7O2Molecular Weight: 465.51
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Kinase_Inhibitor_Library inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Acalabrutinib (ACP-196) is an orally available inhibitor of Bruton’s tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) sPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22693356

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Author: DNA_ Alkylatingdna