Product Name: Vismodegib
Chemical Name: 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide
SMILES Code: O=C(NC1=CC=C(Cl)C(C2=NC=CC=C2)=C1)C3=CC=C(S(=O)(C)=O)C=C3Cl
CAS NO: 298-83-9 Product: AMPPD
Synonym: GDC-0449; GDC 0449; GDC0449
Chemical Formula: C19H14Cl2N2O3S
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).GPCR/G_protein_Compound_Library inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Vismodegib(GDC-0449) is a more potent novel and specific synthetic oral hedgehog pathway inhibitor with an IC50 of 3 nM; also inhibits P-gp with IC50 of 3.0 μM.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21046105