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Product Name: Serdemetan
Chemical Name: N1-(2-(1H-indol-3-yl)ethyl)-N4-(pyridin-4-yl)benzene-1,4-diamine
SMILES Code: C1(NCCC2=CNC3=C2C=CC=C3)=CC=C(NC4=CC=NC=C4)C=C1
CAS NO: 436133-68-5 Product: 6-FAM SE
Synonym: JNJ26854165; JNJ-26854165; JNJ 26854165
Chemical Formula: C21H20N4Molecular Weight: 328.41
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).VEGFR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Serdemetan (JNJ-26854165) is an orally bioavailable, small-molecule HDM2 antagonist with potential antineoplastic activity. HDM2 antagonist JNJ-26854165 inhibits the binding of the HDM2–p53 complex to the proteasome, blocking the degradation of p53; p53 PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18367484

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Author: DNA_ Alkylatingdna