Product Name: PPQ-102
Chemical Name: 7,9-dimethyl-6-(5-methylfuran-2-yl)-11-phenyl-5,6-dihydropyrimido[4′,5′:3,4]pyrrolo[1,2-a]quinoxaline-8,10(7H,9H)-dione
SMILES Code:
CAS NO: 98418-47-4 Product: XEN445
Synonym: CFTR Inhibitor; PPQ102; PPQ 102
Chemical Formula: C26H22N4O3
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Phospholipase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: PPQ-102 (CFTR Inhibitor) is a potent and selective CFTR inhibitor. PPQ-102, completely inhibited CFTR chloride current with IC(50) approximately 90 nM. Patch-clamp analysis confirmed voltage-independent CFTR inhibition by PPQ-102 and showed stabilization PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17974492
