Product Name: HA-1100 HCl
Chemical Name: 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone, monohydrochloride
SMILES Code: OC1=NC=CC2=C1C=CC=C2S(N3CCNCCC3)(=O)=O.Cl
CAS NO: 859498-05-8 Product: iCRT 14
Synonym: HA 1100 hydrochloride; HA1100 hydrochloride; Hydroxyfasudil hydrochloride
Chemical Formula: C14H18ClN3O3S
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Angiotensin-converting Enzyme ACE) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: HA-1100 (Hydroxyfasudil), a cell-permeable hydroxylated metabolite of HA-1077, is a potent inhibitor of Rho-associated kinase (ROCK) (Ki = 150 nM). It less effectively inhibits protein kinase A (Ki = 2.2 μM). It has been used to explore the role of ROCK iPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/11351295
