Product Name: Ruxolitinib
Chemical Name: (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
SMILES Code: N#CC[C@@H](N1N=CC(C2=C3C(NC=C3)=NC=N2)=C1)C4CCCC4
CAS NO: 367273-07-2 Product: 3CAI
Synonym: INCB 018424; INCB018424; INCB-018424
Chemical Formula: C17H18N6
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Aminopeptidase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Ruxolitinib (INC424, INCB18424) is an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which mayPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19137011