Product Name: Vatalanib free base
Chemical Name: N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
SMILES Code: ClC1=CC=C(NC2=NN=C(CC3=CC=NC=C3)C4=C2C=CC=C4)C=C1.[H]Cl.[H]Cl
CAS NO: 633-65-8 Product: AVX 13616
Synonym: PTK787, PTK/ZK, CGP-79787, ZK-222584
Chemical Formula: C20H15ClN4
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).TRP Channel inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR with IC50 of 37 nM in a cell-free assay, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor recePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/14656443
