Product Name: Ponalrestat
Chemical Name: 2-(3-(4-bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid
SMILES Code: O=C(O)CC1=NN(CC2=CC=C(Br)C=C2F)C(C3=C1C=CC=C3)=O
CAS NO: 85416-75-7 Product: BTS
Synonym: ICI-128436; ICI 128436; ICI128436; MK-538; MK 538; MK538
Chemical Formula: C17H12BrFN2O3
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).KLF inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Ponalrestat (MK-538) is an aldose reductase inhibitor. Ponalrestat inhibits cachexia syndrome induced by colon26 adenocarcinoma in mice. Ponalrestat activates lipoprotein lipase (LPL) activity in the adipose tissue and alleviates the cachectic symptoms inPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23028463
