Product Name: Purvalanol A
Chemical Name: (2R)-2-[[6-(3-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]-3-methylbutan-1-ol
SMILES Code: CC(C)C(CO)NC1=NC2=C(C(=N1)NC3=CC(=CC=C3)Cl)N=CN2C(C)C
CAS NO: 1356962-34-9 Product: NSC 23766 (trihydrochloride)
Synonym: NG-60
Chemical Formula: C19H25ClN6O
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Salt-inducible Kinase SIK) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Purvalanol A (NG-60) is a potent CDK inhibitor, which effectively suppresses Src-mediated transformation by inhibiting both CDKs and c-Src. indicating that the activation of CDKs contributes to the c-Src transformation. Purvalanol A suppressed the c-Src aPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/10872825
