Product Name: Varespladib
Chemical Name: 2-((3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yl)oxy)acetic acid
SMILES Code: NC(C(C1=C(CC)N(CC2=CC=CC=C2)C3=C1C(OCC(O)=O)=CC=C3)=O)=O
CAS NO: 1218942-37-0 Product: kb-NB77-78
Synonym: LY 315920; LY315920; LY-315920
Chemical Formula: C21H20N2O5
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Imidazoline Receptor inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Varespladib (LY315920) is a secreted phospholipase A2 (sPLA2) inhibitor (IC50 = 50 – 750 nM for a range of sPLA2 isoforms). Varespladib reduces atherosclerosis and aneurysm formation in ApoE-/- mice and in guinea pigs. Varespladib significantly reduPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/ 9484812
