Product Name: PF-573228
Chemical Name: 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone
SMILES Code: O=C1NC2=C(C=C(NC3=NC=C(C(F)(F)F)C(NCC4=CC=CC(S(=O)(C)=O)=C4)=N3)C=C2)CC1
CAS NO: 1380672-07-0 Product: AZD-9291 (dimesylate)
Synonym: PF573228; PF 573228
Chemical Formula: C22H20F3N5O3S
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Phosphatase_Inhibitor_Cocktail_II inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: PF-573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50= 4 nM). Displays 50 – 250-fold selectivity for FAK over other protein kinases.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17534442
