Product Name: Z-LEHD-FMK
Chemical Name: methyl (4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-4-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-oxopentanoate
SMILES Code: CC(C)CC(C(=O)NC(CCC(=O)OC)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC2=CC=CC=C2
CAS NO: 292605-14-2 Product: Firocoxib
Synonym: Caspase-9 inhibitor
Chemical Formula: C32H43FN6O10
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Natural_Product_Library_ inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Z-LEHD-FMK is a specific and irreversible inhibitor of caspase-9, which is an initiator caspase and plays an important role in the mitochondrial death pathway. Caspase-9 is activated during programmed cell death and cleaves procaspase-7 and procaspase-3.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16204078
