Product Name: Refametinib
Chemical Name: (S)-N-(3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide
SMILES Code: O=S(C1(C[C@H](O)CO)CC1)(NC2=C(OC)C=C(F)C(F)=C2NC3=CC=C(I)C=C3F)=O
CAS NO: 1292310-49-6 Product: Lomitapide (mesylate)
Synonym: BAY 869766; BAY 86-97661; RDEA-119; RDEA119
Chemical Formula: C19H20F3IN2O5S
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Kinase_Inhibitor_Library inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Refametinib (BAY 86-97661; RDEA-119) is an orally bioavailable selective MEK inhibitor with potential antineoplastic activity. MEK inhibitor RDEA119 specifically inhibits mitogen-activated protein kinase kinase 1 (MAP2K1 or MAPK/ERK kinase 1), resulting iPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15689157
