Product Name: JK 184
Chemical Name: N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine
SMILES Code: CCOC1=CC=C(C=C1)NC2=NC(=CS2)C3=C(N=C4N3C=CC=C4)C
CAS NO: 656247-18-6 Product: WS6
Synonym:
Chemical Formula: C19H18N4OS
Appearance: Solid powderWeb Site：Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Endocrinology inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: JK 184 is a potent downstream hedgehog (Hh) signaling inhibitor that prevents Gli-dependent transcriptional activity (IC50 = 30 nM). Exhibits antiproliferative activity in a range of cancer cell lines (GI50 = 3 – 21 nM) and in human xenografts in viPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16510597
