Product Name: LY2835219
Chemical Name: N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine;methanesulfonic acid
SMILES Code: CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F.CS(=O)(=O)O
CAS NO: 149888-94-8 Product: Remodelin (hydrobromide)
Synonym: ABEMACICLIB; CDK4/6 dual inhibitor; LY 2835219; LY-2835219
Chemical Formula: C28H36F2N8O3S
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).YAP inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: LY2835219 (Abemaciclib) is orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. LY2835219 inhibits CDK4 and CDK6 with low nanomolar potePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/2992365
