Product Name: Apatinib
Chemical Name: N-[4-(1-cyanocyclopentyl)phenyl]-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide
SMILES Code: C1CCC(C1)(C#N)C2=CC=C(C=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4
CAS NO: 1416258-16-6 Product: RS102895
Synonym: YN-968D1; YN 968D1; YN968D1
Chemical Formula: C24H23N5O
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).FGFR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Apatinib (YN968D1) is a potent inhibior of the VEGF signaling pathway with the IC50 value of 1nM for VEGFR-2 in in vitro enzyme experiments. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-sPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17284576
