Product Name: LY-3177833
Chemical Name: (3R)-3-(5-Fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-1H-isoindol-1-one
SMILES Code: O=C1N[C@@](C)(C2=NC=NC=C2F)C3=C1C=C(C4=CNN=C4)C=C3
CAS NO: 328968-36-1 Product: Amikacin (sulfate)
Synonym: LY 3177833; LY3177833
Chemical Formula: C16H12FN5O
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).c-Kit inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: LY-3177833 is a clinical stage, orally available, potent and selective inhibitor of CDC7 (Cell Division Cycle 7-related Protein Kinase), inhibiting CDC7/DBF4 I and pMCM2 (S53) with IC50 values of 3.3 nM and 290 nM, respectively. The inhibition profoundly PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/%2015056863