Product Name: IPI-549
Chemical Name: (S)-2-amino-N-(1-(8-((1-methyl-1H-pyrazol-4-yl)ethynyl)-1-oxo-2-phenyl-1,2-dihydroisoquinolin-3-yl)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
SMILES Code: O=C1N(C2=CC=CC=C2)C([C@@H](NC(C3=C(N=CC=C4)N4N=C3N)=O)C)=CC5=CC=CC(C#CC6=CN(C)N=C6)=C51
CAS NO: 1155419-89-8 Product: Isosorbide mononitrate
Synonym: IPI 549; IPI549
Chemical Formula: C30H24N8O2
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Btk inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: IPI-549 is a potent and selective PI3Kγ Inhibitor with IC50 of 16 nM, which shows no significant inhibition for a panel of 468 mutant and non mutant protein and lipid kinases (including Class II PI3K isoforms) at 1 µM. IPI-549 demonstrates favorable pharmPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/10817750
