Product Name :
Peptide T
CAS NO. :
1610056-01-3
Formula :
C37H56F3N9O18
Molecular Weight::
971.89
Target:
HIV
Serial Number:
Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr
Short serial number :
ASTTTNYT
Purity:
95%
Description :
Peptide T (TFA) is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor.Peptide T acetate is an HIV entry inhibitor from the V2 region of HIV-1 gp120 that acts by blocking chemokine-5 receptors (CCR5), currently under clinical trials for the treatment of HIV-related neurological and constitutional symptoms.
References:
[1]. Immunomodulatory effects of peptide T on Th 1/Th 2 cytokines. [2].Peptide T does not ameliorate experimental autoimmune encephalomyelitis (EAE) in Lewis rats. [3].Peptide T inhibits HIV-1 infection mediated by the chemokine receptor-5 (CCR5).
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