Product Name :
MMP-8 Inhibitor
CAS NO. :
120928-08-7
Formula :
C13H24N4O4
Molecular Weight::
300.35
Target:
Serial Number:
Pro-Leu-Gly-NHOH
Short serial number :
PLG-NHOH
Purity:
95%
Description :
Affinity ligand for the purification of human collagenases. Inhibitor of MMP-8, Ki 19 μM (Grams et al., 1995).
References:
[1]. Activity-based enrichment of matrix metalloproteinases using reversible inhibitors as affinity ligands. [2]. Human meprin alpha and beta homo-oligomers: cleavage of basement membrane proteins and sensitivity to metalloprotease inhibitors. [3].X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design.
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