Caspase 1 Inhibitor II

References:
[1]. LPS challenge in D-galactosamine-sensitized mice accounts for caspase-dependent fulminant hepatitis, not for septic shock. [2]. Caspase-1-inhibitor ac-YVAD-cmk reduces LPS-lethality in rats without affecting haematology or cytokine responses. [3].Crystallization and preliminary X-ray diffraction analysis of a recombinant cysteine-free mutant of crmA. [4]. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. [5]. Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival.