Prolyl endopeptidase Inhibitor II; Z-Pro-Pro-CHO | DNA

Product Name :
Prolyl endopeptidase Inhibitor II; Z-Pro-Pro-CHO

CAS NO. :
86925-97-5

Formula :
C18H22O4N2

Molecular Weight::
330.38

Target:

Serial Number:
Cbz-Pro-Pro-CHO

Short serial number :
Z-PP-CHO

Purity:
95%

Description :
Z-PP-CHO dimethylacetal was shown to be a potent inhibitor of prolyl endopeptidase (PEP), a cytoplasmic serine endoprotease (IC₅₀= 120 nM). It is suggested that PEP inhibitors could be useful for the treatment of cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer’s disease.

References:
[1].In situ prolyl oligopeptidase activity assay in neural cell cultures. [2].Structure-activity relationships of αs-casein peptides with multifunctional biological activities. [3]. Prolyl endopeptidase is revealed following SILAC analysis to be a novel mediator of human microglial and THP-1 cell neurotoxicity. [4]. Prolyl oligopeptidase stimulates the aggregation of alpha-synuclein.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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