Product Name: CFI-400945 free base
Chemical Name: (1S,2R)-2-[3-[(1E)-2-[4-[[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5′-methoxy-spiro[cyclopropane-1,3′-[3H]indol]-2′(1’H)-one
SMILES Code: C[C@@H]1O[C@H](C)CN(CC2=CC=C(/C=C/C3=NNC4=C3C=CC([C@H]5[C@@]6(C(C=C(OC)C=C7)=C7NC6=O)C5)=C4)C=C2)C1
CAS NO: 1564286-55-0 Product: NLG919
Synonym: CFI400945; CFI 400945
Chemical Formula: C33H34N4O3
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).NF-kappa)B inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: CFI-400945 is an orally available fumarate salt form of CFI-400945, a polo-like kinase 4 (PLK4) inhibitor with potential antineoplastic activity. Upon oral administration, polo-like kinase 4 inhibitor CFI-400945 selectively inhibits PLK4, which results inPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17977962