Product Name :
MMP-8Substrate, Fluorogenic(NeutrophilCollagenaseS
CAS NO. :
135662-05-4
Formula :
C49H63N13O13
Molecular Weight::
1042.10
Target:
MMP
Serial Number:
Dnp-Pro-Leu-Ala-Tyr-Trp-Ala-Arg-OH
Short serial number :
Dnp-PLAYWAR
Purity:
95%
Description :
Dnp PLAYWAR is a fluorescent substrate of matrix metalloproteinase-8 (MMP-8) and MMP-26. The activity of MMP-8 and MMP-24 can be quantified by measuring tryptophan fluorescence, which is not affected by peptide hydrolysis, which removes the N-terminal dinitro group.
References:
[1]. Morla S, et al. Discovery of Sulfated Small Molecule Inhibitors of Matrix Metalloproteinase-8. Biomolecules. 2020 Aug 9;10(8):1166.
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