Product Name :
醋酸生长抑素
CAS NO. :
54472-66-1
Formula :
C78H108N18O21S2
Molecular Weight::
1697.9
Target:
Serial Number:
H-Ala-Gly-Cys(1)-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys(1)-OH.CH3CO2H
Short serial number :
AGCKNFFWKTFTSC
Purity:
≥98%
Description :
生长抑素醋酸酯(又称生长激素抑制激素(GHIH)或生长激素释放抑制因子(SRIF))或生长激素释放抑制激素是一种调节内分泌系统并通过与G蛋白相互作用影响神经传递和细胞增殖的肽激素。结合生长抑素受体，抑制许多次生激素的释放。生长抑素调节胰岛素和胰高血糖素。醋酸生长抑素抑制和刺激甲状腺，分泌胰岛素和胰高血糖素。可通过试餐和五肽胃泌素抑制分泌，刺激胃酸、胃蛋白酶，抑制胃泌素的释放。
References:
[1]Antiproliferative effect of octretide on gastric cancer cells m ediated by inhibition of telom erase.GAO S,YU BP,LI Y,et al.World Journal of Gastroenterology.2003 [2]Antiproliferative activ-ity induced by the som atostatin analogue,TT-232on hum an pan-creatic cancer cells.LEE JU,H OSOTANI R,W ADA M,et al.European Journal of Cancer.2002 [3]Som atostatin analog RC-160inhibits growth of CFPAC-1hum an pancreatic cancer cells in vitro and intracellular production of cyclic adenosine m onophosphate.QIN Y,ERTL T,GROOT K,et al.International Journal of Cancer.1995 [4]Inhibition of som atostatin analog Octreotide on hum an gastric cell M KN45in vitro.W ANG XB,W ANG X,ZANG NZ.Shijie H uaren Xiaohua Zazhi.2002 [5]Inhibition effects of som ato-statin on hepatocellular carcinom a in vitro and in vivo.H UA YP,LIANG LJ,H UANG JF.China Journal of M odern M edicine.2003
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