Product Name: SNX-2112
Chemical Name: 4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-(((1r,4r)-4-hydroxycyclohexyl)amino)benzamide
SMILES Code: O=C(N)C1=CC=C(N2N=C(C(F)(F)F)C3=C2CC(C)(C)CC3=O)C=C1N[C@H]4CC[C@H](O)CC4
CAS NO: 1627503-67-6 Product: SGC0946
Synonym: SNX2112; SNX 2112; PF 04928473; PF-04928473; PF04928473
Chemical Formula: C23H27F3N4O3
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Serotonin Transporter inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: SNX-2112 (PF04928473) is a potent synthetic heat shock protein 90 inhibitor with an IC50 of 0.92 μM for K562 cells. The heat shock protein 90 (Hsp90) chaperone not only regulates the conformational maturation but also stables the structures of oncogenic kPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21985091
