Product Name :
Mastoparan X
CAS NO. :
72093-22-2
Formula :
C73H126N20O15S1
Molecular Weight::
1555.97
Target:
Endogenous Metabolite
Serial Number:
Ile-Asn-Trp-Lys-Gly-Ile-Ala-Ala-Met-Ala-Lys-Lys-Leu-Leu-NH2
Short serial number :
INWKGIAAMAKKLL-NH2
Purity:
95%
Description :
Mastoparan X has been isolated from the venom of Vespa xanthoptera. It has been suggested that mastoparan enhances the transport of Ca²⁺, Na⁺ and K⁺ ions through black membrane.It is a G protein activator peptide that binds to Gi and Go. It also binds with high affinity to calmodulin (Kd~0.9 nM) and inhibits sarcoplasmic reticulum Ca2+-ATPase (Ki=4.4 mM).
References:
[1]. Wakamatsu K, et al. Membrane-bound conformation of mastoparan-X, a G-protein-activating peptide. Biochemistry. 1992 Jun 23;31(24):5654-60. [2]. Whiles JA, et al. Orientation and effects of mastoparan X on phospholipid bicelles. Biophys J. 2001 Jan;80(1):280-93.
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