Product Name :
Peptide C105Y、[Cys58]105Y, α1-antitrypsin (358-374)
CAS NO. :
247572-63-0
Formula :
C97H148N20O23S1
Molecular Weight::
1994.40
Target:
others
Serial Number:
Cys-Ser-Ile-Pro-Pro-Glu-Val-Lys-Phe-Asn-Lys-Pro-Phe-Val-Tyr-Leu-Ile-OH
Short serial number :
CSIPPEVKFNKPFVYLI
Purity:
95%
Description :
Peptide C105Y TFA, a synthetic and cell-penetrating peptide based on the amino acid sequence corresponding to residues 359-374 of β-antitrypsin, enhances gene expression from DNA nanoparticles.It is a synthetic peptide based on the sequence corresponding to residues 359 to 374 of α1-antitrypsin. C105Y can penetrate cell membrane rapidly, enter the cytoplasm, and localize to the nucleus and nucleolus of live culture cells. C105Y peptide enters the nucleolus very rapidly in an energy-dependent manner. Membrane transport and nuclear localization are energy-independent. It enhances gene expression in DNA nanoparticles.Peptide C105Y is a cell-penetrating peptide based on the α1-antitrypsin 359-374 amino acids sequence, which enhances gene expression of DNA nanoparticles.
References:
[1]. Rhee M, et al. Mechanism of uptake of C105Y, a novel cell-penetrating peptide. J Biol Chem. 2006 Jan 13;281(2):1233-40.
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