Product Name :
TAT-NSF700 Fusion Peptide
CAS NO. :
Formula :
C188H318N62O45
Molecular Weight::
4166.92
Target:
others
Serial Number:
Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Gly-Leu-Leu-Asp-Tyr-Val-Pro-Ile-Gly-Pro-Arg-Phe-Ser-Asn-Leu-Val-Leu-Gln-Ala-Leu-Leu-Val-Leu-OH
Short serial number :
YGRKKRRQRRRGGGLLDYVPIGPRFSNLVLQALLVL
Purity:
95%
Description :
It is a N-Ethyl-maleimide-sensitive factor (NSF) inhibitor fusion polypeptide, which is fused from the 11 amino acid cell permeable HIV transactivation regulatory protein (TAT) domain to the 22 amino acid NSF domain. TAT-NSF700 inhibits thrombin-induced exocytosis of endothelial cells in a dose-responsive manner.
References:
[1]. Shi HS, et al. Ca2+-dependent recruitment of voltage-gated sodium channels underlies bilirubin-induced overexcitation and neurotoxicity. Cell Death Dis. 2019 Oct 10;10(10):774.
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