Product Name :
NFF-3
CAS NO. :
158584-09-9
Formula :
C78H110O20N22
Molecular Weight::
1675.84
Target:
MMP
Serial Number:
MCA-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2
Short serial number :
Mca-RPKPVE-Nva-WR-K(Dnp)-NH2
Purity:
95%
Description :
The FRET substrate Mca-RPKPVE-Nva-WRK(Dnp) amide was hydrolyzed rapidly by stromelysin 1 (MMP-3) with kcat/Km= 218000 M⁻¹s⁻¹ and very slowly by gelatinase B (MMP-9) (kcat/Km= 10100 M⁻¹s⁻¹). There was no hydrolysis by MMP-1 and MMP-2.
References:
[1]. Giricz O, et al. Comparison of metalloproteinase protein and activity profiling. Anal Biochem. 2011 Feb 1;409(1):37-45.
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